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Notably, the present narrative review is an extension of a previous review article that covered polyphenols and/or phytoestrogens that included daidzein, equol, genistein, and resveratrol as supplemental therapies for skin aging, which was published in Dermatology and Therapy earlier this year by Lephart (2025) [9]

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Sublingual administration offers a middle ground, providing better absorption than oral routes while avoiding injection discomfort

Verhoef et al, 1996) increase the cardiovascular risk